THE PRINCIPLE OF DETOXIFICATION
Detoxification, more commonly called “detox”, is a natural process that neutralizes and eliminates the toxins that enter the body, so as to find normal physiological functions (enhanced immunity, better quality of sleep, vitality, hormonal balance …).
Detoxification involves multiple reactions and involves 5 emunctory organs, each having functions of barrier, neutralization and elimination: the liver, kidneys, intestines, lungs and skin. These organs will limit the entry of toxic and carcinogenic substances into the body (barrier role), neutralize them and eliminate them.
The liver plays a major role in the process of detoxifying the body. Its functions are many, but one of the main is to neutralize toxic compounds by allowing their elimination.
The process of detoxification at the level of the liver is carried out in 2 stages :
The first step is to neutralize the toxic compounds by producing intermediate molecules still harmful. This step depends on an enzymatic system: cytochromes P450 (CYPs);
The second step inactivates these intermediate molecules and involves other enzymes (such as Glutathione-S or Glucuro-Transferase);
Finally, these neutralized compounds will be eliminated either by the urine via the renal activity, or in the stool via the bile and the intestine (phase 3 or elimination stage).
However, in the face of the increase of toxins in our environment, the liver saturates and no longer performs its function optimally. Via the circulation, it will release the toxins not eliminated in the tissues and target organs where they will be stored.
This is why it is necessary to perform detoxification treatments to support the natural function of liver detoxification. It is the assurance of a healthy body, especially in times of weight loss where the release of toxic is massive.